|
KMID : 0377519780030010011
|
|
Chung-Ang Journal of Medicine
1978 Volume.3 No. 1 p.11 ~ p.19
|
|
|
Effects of Temperature on Electrical and Contractile Properties of Rabbit Papillary Muscles
|
|
Chung Hak-Ki
Uhm Dae-Yong
Rhee Sang-Don
|
|
|
Abstract
|
|
|
|
The effect of temperature on transmembrane potential and contractile tension of the papillary muscle was investigated in the rabbits perfusing with bicarbonate buffered solution. Lowering of temperature from 36℃ to 24℃ decreased resting membrane potential from -88.5±1.1 to 71.0±3.4mV, increased overshoot potential from 16.1±0.5 to 23.2±0.7mV. Therefore, the action potential decreased slightly from 104.6±1.5 to 94.2±4.0mV. And duration of action potential increased from 123±1.0m sec at 36℃ to 345±5.1m sec at 24℃. Contractile tension increased consistently as temperature of bicarbonate-buffered solution lowered. The increment was due to prolongation of active state, not due to increase in dT/dt, resulting in prolongation of duration of contraction. The activation energies obtained from action potential duration and duration of contraction were 19.200 and 23.700 cal/m/degree.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|